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Source Data for Figure 2[LSA-2023-02505_SdataF2.pptx] Boosting NAD + levels during pregnancy improves pregnancy outcomes in an inflammation-driven PE model As NAD + depletion was observed in placentas from cases of inflammation-driven PE, and NAD + supplementation in vitro improved human trophoblast health and function under pro-inflammatory conditions, we next sought to determine whether NR could be used to prevent the development of PE-like clinical features in a rat model of inflammation-driven PE

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